Steroids and derivatives
Sigma Aldrich Fine Chemicals Biosciences Prednisone United States Pharmacopeia (USP) Reference Standard | 53-03-2 | MFCD00003608 | 250MG
Prednisone United States Pharmacopeia (USP) Reference Standard | Mol Wt: 358.43 | 53-03-2 | MFCD00003608 | 250MG
Sigma Aldrich Fine Chemicals Biosciences Prednisone | 53-03-2 | MFCD00003608 | 1 g
Prednisone | Purity: ≥98% | Mol Wt: 358.43 | 53-03-2 | MFCD00003608 | 1 g
Sigma Aldrich Fine Chemicals Biosciences Prednisone >=98% | 53-03-2 | MFCD00003608 | 10G
Prednisone >=98% | Purity: >=98% | Mol Wt: 358.43 | 53-03-2 | MFCD00003608 | 10G
Sigma Aldrich Fine Chemicals Biosciences Cholic acid | 81-25-4 | MFCD00003672 | 60 mg
Cholic acid | Mol Wt: 408.57 | 81-25-4 | MFCD00003672 | 60 mg
Medchemexpress LLC Glycocholic acid | 475-31-0 | 465.62 | 5 G
Glycocholic acid is a bile acid with anticancer activity, targeting pump resistance-related and non-pump resistance-related pathways. It is for research use only and not sold to patients.
- Appearance: Solid
- Color: White to off-white
- Classification: Steroids
- Initial source: Endogenous metabolite, human gut microbiota metabolites
- Increases the cytotoxicity of epirubicin
- Modulates P-gp and MRPs as well as regulating apoptosis-related pathways
![Medchemexpress LLC Glycine, N-[(3α,5β, 7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1) | 863-57-0 | 487.60 | 500 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000416267.png-250.jpg)
Medchemexpress LLC Glycine, N-[(3α,5β, 7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1) | 863-57-0 | 487.60 | 500 MG
Glycocholic acid sodium is an orally active bile acid that exhibits anticancer activity by targeting both pump resistance-related and non-pump resistance-related pathways.
- Orally active bile acid
- Possesses anticancer activity
- Targets pump resistance-related and non-pump resistance-related pathways
Cambridge Isotope Laboratories GLYCOCHOLIC ACID (2,2,4,4-D4, 98%) (CONTAINS ~4% WATER), 10 MG
GLYCOCHOLIC ACID (2,2,4,4-D4, 98%) (CONTAINS ~4% WATER), 10 MG
Medchemexpress LLC Rufinamide-d2 | 1129491-38-8 | C10H6D2F2N4O | 1 MG
Rufinamide-d2 (CGP 33101-d2) is a deuterium-labeled Rufinamide, an orally active antiepileptic compound. It inhibits Na+ current activation and neuronal hyperexcitability, exhibiting anticonvulsant effects. This compound is utilized in the study of Lennox-Gastaut syndrome, with its deuteration influencing pharmacokinetic and metabolic profiles.
- Inhibits Na+ current activation
- Inhibits neuronal hyperexcitability
- Provides anticonvulsant effects
- Used in the study of Lennox-Gastaut syndrome
- Deuterium-labeled for tracer applications
- Influences pharmacokinetic and metabolic profiles
Medchemexpress LLC Bazedoxifene acetate | 198481-33-3 | 99.9% | C32H38N2O5 | 1 ML
Bazedoxifene acetate is an oral, nonsteroidal selective estrogen receptor modulator (SERM) primarily used as a laboratory chemical for research, especially concerning osteoporosis and pancreatic cancer. It functions as an inhibitor of IL-6/GP130 protein-protein interactions and is stable under recommended storage conditions.
- Oral, nonsteroidal selective estrogen receptor modulator (SERM)
- Inhibits ERα with IC50 of 23 nM and ERβ with IC50 of 99 nM
- Utilized for research on osteoporosis
- Functions as an inhibitor of IL-6/GP130 protein-protein interactions
- Suitable for pancreatic cancer research
- Appears as a solid
- Stable under recommended storage conditions
Medchemexpress LLC Estrone 3-methyl ether | 1624-62-0 | 97.38% | C19H24O2 | 5 MG
Estrone 3-methyl ether is a synthetic intermediate used in the synthesis of estrogen receptor modulators.
- Used in the synthesis of estrogen receptor modulators
- Molecular weight: 284.39
- Molecular formula: C19H24O2
- CAS number: 1624-62-0
- Purity: 97.38%
- Appearance: Solid, white to off-white
- Storage (Powder): -20°C for 3 years; 4°C for 2 years
- Storage (In solvent): -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Melatonin-d3 (N-Acetyl-5-methoxytryptamine-d3) | 90735-69-6 | 99.1% | C13H13D3N2O2 | 5 MG
Melatonin-d3 is the deuterium labeled version of Melatonin. Melatonin is a hormone that activates melatonin receptors, playing a role in sleep and possessing antioxidative and anti-inflammatory properties. It is also identified as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells by alleviating endoplasmic reticulum stress.
- Used as a tracer
- Serves as an internal standard for quantitative analysis
- Stable heavy isotopes for drug development quantitation
- Deuteration can influence pharmacokinetic and metabolic profiles
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solvent storage: -80°C for 6 months, -20°C for 1 month
Enzo Life Sciences 20-Hydroxyecdysone (50mg). CAS: 5289-74-7
Most widely occurring ecdysteroid in both plant and animal species. Controls cell death during metamorphosis of Drosophila melanogaster. Alternative name: beta-Ecdysone, 2beta,3beta,14alpha,20R,22R,25-Hexahydroxy-5beta-cholest-7-en-6-one, Ecdysterone. Purity: ≥95% HPLC. Appearance: White powder. Solubility: Soluble in water, 100% ethanol, methanol, DMSO and acetic acid. Long Term Storage: -20°C.
Apexbio Technology LLC Fluorometholone Acetate 3801-06-7 50mg
Fluorometholone Acetate (CAS 3801-06-7) is a synthetic glucocorticoid corticosteroid designed for the modulation of inflammatory responses Acting through binding to the glucocorticoid receptor it regulates the transcription of anti-inflammatory proteins while suppressing pro-inflammatory gene expression This compound is extensively utilized in ophthalmic research for modeling and investigating steroid-responsive inflammatory processes in ocular tissues Its application facilitates the study of corticosteroid-mediated pathways in eye inflammation and aids in the evaluation of anti-inflammatory interventions in preclinical settings